Thanks for stopping by! We're excited you're here!

Led by Dr. Dan Sprague, we are a new chemistry and pharmacology lab in the Department of Biochemistry and Molecular Biology at the Medical University of South Carolina. Broadly, we are interested in discovering new druggable targets across a wide range of diseases.

To do so, we dig into illuminating novel, or understudied, signaling and biosynthesis pathways. We then design, synthesize, and optimize new small molecules that target key points within these pathways. These molecules can then be used as tools and preclinical candidates, allowing us to learn more about different diseases.

At the moment, our interests span the gambit from Neglected Tropical Diseases, to cancer, to neurotransmitter signaling -- and sometimes the combination of all three!! Ultimately, the goal is to develop translational science -- from bench, to bedside, and then back to the bench for further optimization.

Please, take a look around, and feel free to reach out if anything catches your eye!