Led by Dr. Dan Sprague, we are a chemical biology lab in the Department of Biochemistry and Molecular Biology at the Medical University of South Carolina. Broadly, we are interested in discovering new druggable targets across a wide range of diseases. 

To do so, we dig into illuminating novel, or understudied, signaling and biosynthesis pathways. We tease apart their role in disease, and when relevant, we use them as new targets around which to design and discover new small molecules. These molecules can then be used as tools and preclinical candidates, allowing us to learn more about different diseases.

At the moment, our interests are in cancer, neglected tropical diseases, and neurotransmitter signaling (and sometimes, the combination of all three!). Ultimately, the goal is to develop translational science -- from bench, to bedside, and then back to the bench for further optimization. 

We are also avid collaborators, and have collaborations in everything from pediatric cancers to natural products chemistry. Science is better when everyone works together!

Please, take a look around, and feel free to reach out if anything catches your eye!