Projects
We are consistently exploring new signaling to better understand physiology and to uncover potential drug targets. Click on the links below to learn more about what we spend time thinking about!
GPCRs and Other Targets for Neglected Tropical Diseases
1-in-6 people are infected with a neglected tropical disease (~1.4 billion people)! Though they are incredibly common across the globe, they are notoriously understudied. We study the organisms causing these diseases, and discover new ways to treat them.
Precision Therapeutics in Oncology
About 40% of people will develop cancer in their lifetime, and nearly everyone has been impacted by cancer in some way. We study cancer mutations to learn how to make more targeted cancer therapeutics by exploiting novel pathways and synthetic lethality.
Biased Signaling in Neuropharmacology
Not all receptor signaling is created equal. This is especially true with GPCRs. We are interested in exploring how we can fine-tune ligand-receptor-signal pathways to understand physiology, deorphanize receptors, and develop new drugs.